@article{87816,
  keywords = {chemotaxis, Recombinant Proteins, Escherichia coli, Biophysics, Models, Biological, Luminescent Proteins, Microscopy, Fluorescence, Green Fluorescent Proteins, Biophysical Phenomena},
  author = {Sungsu Park and Peter Wolanin and Emil Yuzbashyan and Hai Lin and Nicholas Darnton and Jeffry Stock and Pascal Silberzan and Robert Austin},
  title = {Influence of topology on bacterial social interaction.},
  abstract = { The environmental topology of complex structures is used by Escherichia coli to create traveling waves of high cell density, a prelude to quorum sensing. When cells are grown to a moderate density within a confining microenvironment, these traveling waves of cell density allow the cells to find and collapse into confining topologies, which are unstable to population fluctuations above a critical threshold. This was first observed in mazes designed to mimic complex environments, then more clearly in a simpler geometry consisting of a large open area surrounding a square (250 x 250 microm) with a narrow opening of 10-30 microm. Our results thus show that under nutrient-deprived conditions bacteria search out each other in a collective manner and that the bacteria can dynamically confine themselves to highly enclosed spaces. },
  year = {2003},
  journal = {Proc Natl Acad Sci U S A},
  volume = {100},
  pages = {13910-5},
  month = {11/2003},
  issn = {0027-8424},
  doi = {10.1073/pnas.1935975100},
  language = {eng},
}